Industry Sector

Pharmaceuticals — US PTAB Patent Cases

247 decisions indexed

Page 6 of 9 · 247 total

patent instituted · Jan 5, 2025

AZURITY PHARMACEUTICALS, INC. v.Helsinn Healthcare S.A.

· IPR2025-00947

AZURITY PHARMACEUTICALS successfully convinced the PTAB to institute IPR proceedings against Helsinn Healthcare S.A.'s patent covering anti-emetic agents for oncology treatment. The Board found a reasonable likelihood that numerous claims would be unpatentable under 35 U.S.C. § 103 based on prior art references.

patent instituted · Jan 5, 2025

AZURITY PHARMACEUTICALS, INC. v.Helsinn Healthcare S.A.

· IPR2025-00945

AZURITY PHARMACEUTICALS successfully petitioned to institute IPR proceedings against Helsinn Healthcare S.A.'s anti-emetic patent (8623826). The Board found a reasonable likelihood of prevailing on independent claim 19, allowing the challenge based on obviousness over prior art like MASCC and Hoffmann.

patent instituted · Jan 5, 2025

AZURITY PHARMACEUTICALS, INC. v.Helsinn Healthcare S.A.

· IPR2025-00946

AZURITY PHARMACEUTICALS, INC. successfully secured institution of its IPR against Helsinn Healthcare S.A.'s patent (9186357) for anti-emetic agents. The Board found a reasonable likelihood that several claims would be unpatentable over prior art, specifically regarding the combination of triple-drug CINV treatment and superior NK antagonists.

patent · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

Merck has filed a post‑grant review petition challenging Halozyme’s enzyme patent, arguing the claims lack adequate written description and enablement. The reply emphasizes functional language and the impossibility of testing the claimed 1,059+ PH20 variants.

patent · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

Merck defends its PH20 enzyme patent in a PTAB Director Review proceeding, arguing that the claims satisfy §112 written description and enablement and that Halozyme's claim‑construction objections are unfounded. The petitioner also contends that Fintiv factors do not justify discretionary denial.

patent · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

Halozyme seeks Director Review to overturn the PTAB’s institution of a post‑grant review of its ’035 enzyme patent. The petition contends the Board mis‑interpreted claim language and mis‑applied eligibility standards, and argues that Fintiv factors demand denial of institution.

patent · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

Halozyme has sought a Director Review of the PGR, and Merck has 5 business days to file a brief response without new evidence.

patent denied · Dec 27, 2024

Biofrontera Incorporated et al. v.Sun Pharmaceutical Industries, Inc.

· IPR2025-00287

The USPTO denied Biofrontera's request for rehearing of the decision that refused to institute its IPR against Sun Pharmaceutical's patent 11,446,512. The Board affirmed the discretionary denial, leaving the patent unchallenged.

patent · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

Merck has filed a Post‑Grant Review petition challenging Halozyme’s U.S. Patent 12,123,035 covering PH20 hyaluronidase mutants. The petition asserts lack of written description, lack of enablement, and obviousness of the claims. The Board has yet to decide whether to institute the trial.

patent instituted · Dec 27, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00009

The PTAB instituted the PGR petition challenging Halozyme's patent covering modified PH20 polypeptides. The Board found that the claims were not sufficiently supported by the specification regarding enablement and obviousness, despite Petitioner's arguments about the genus size.

patent · Dec 24, 2024

Ajinomoto Co., Inc. v.AbTis Co., Ltd.

· IPR2025-00283

Ajinomoto has filed an IPR petition challenging AbTis’s U.S. Patent 11,896,675 covering site‑specific antibody‑drug conjugates. The petitioner alleges lack of written description, improper priority, and that all 13 claims are anticipated or obvious over several pre‑grant publications and conference disclosures. The petition seeks cancellation of every claim.

patent instituted · Dec 24, 2024

ITM Isotope Technologies Munich SE v.The Johns Hopkins University et al.

· PGR2025-00012

ITM Isotope Technologies Munich SE challenged The Johns Hopkins University's claims regarding FAP-α targeting moieties based on obviousness and patentability issues (103/112). The Board instituted the PGR, finding that the claims face significant challenges related to enablement and indefiniteness.

patent · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Halozyme has filed a Director Review request asking the PTAB to overturn its institution of a post‑grant review of the ’600 hyaluronidase protein patent, arguing procedural errors and an improper claim construction.

patent instituted · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Merck Sharp & Dohme LLC filed a response defending the institution of a post‑grant review of Halozyme’s enzyme patent. The brief rebuts Halozyme’s eligibility, claim‑construction, and Fintiv arguments, emphasizing that the Board’s earlier findings remain sound.

patent · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Merck files a PGR petition challenging Halozyme’s protein‑based contraceptive patent, arguing the claims lack written description and enablement. The reply emphasizes that the specification does not support the broad genus of modified PH20 polypeptides claimed.

patent denied · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

The USPTO Director denied Merck’s request for a review of the PTAB’s institution decisions in four Halozyme patent cases, leaving the institution findings intact.

patent instituted · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Merck Sharp & Dohme LLC successfully challenged Halozyme, Inc.'s patent on modified PH20 polypeptides in a PGR proceeding. The Board found likelihood of prevailing based on arguments regarding the genus's scope and potential lack of enablement/obviousness.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Halozyme seeks Director Review to overturn the PTAB’s institution of a post‑grant review against its hyaluronidase patent, arguing filing‑date errors, improper claim construction, and Fintiv factors favoring denial.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck has filed a petition to invalidate Halozyme’s ’298 patent covering modified PH20 polypeptides, arguing the claims lack written description and enablement. The reply attacks Halozyme’s reliance on functional language and disclaimed dependent claims.

patent instituted · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck challenges Halozyme’s request for Director review after the PTAB instituted a post‑grant review of U.S. Patent 12,018,298 covering modified PH20 polypeptides. Merck argues the eligibility and claim‑construction issues are meritless and that the Fintiv factors favor institution.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck challenges Halozyme’s broad PH20 hyaluronidase patent, asserting lack of written description, enablement, and obviousness of the claimed protein variants.

patent instituted · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck Sharp & Dohme LLC successfully petitioned the PTAB against Halozyme, Inc.'s '298 patent covering modified PH20 polypeptides. The Board granted institution despite challenges based on Written Description and Enablement, allowing the dispute to proceed to trial.

patent · Nov 20, 2024

Samsung Bioepis Co., Ltd. v.Regeneron Pharmaceuticals, Inc.

· IPR2025-00176

Samsung Bioepis has filed an IPR petition challenging 48 claims of Regeneron’s anti‑VEGF ophthalmic formulation patent, arguing the claims are obvious over prior‑art formulations and presentation data.

patent denied · Nov 20, 2024

Samsung Bioepis Co., Ltd. v.Regeneron Pharmaceuticals, Inc.

· IPR2025-00176

Samsung Bioepis sought to invalidate numerous claims of Regeneron Pharmaceuticals' ophthalmic formulations using grounds of obviousness (103). The PTAB denied institution based on a holistic Fintiv analysis, citing significant overlap with ongoing district court and MDL proceedings.

patent · Nov 18, 2024

Azurity Pharmaceuticals, Inc. v.EXELIXIS, INC.

· IPR2025-00210

Azurity Pharmaceuticals has filed an IPR petition seeking cancellation of claims 1‑3 of Exelixis’s U.S. Pat. 11,298,349 covering oral cabozantinib (L)-malate formulations. The petition alleges anticipation by the earlier Wilson patent and obviousness over Brown, Kubo and Remington, while arguing that discretionary denial factors do not apply.

patent denied · Nov 18, 2024

Azurity Pharmaceuticals, Inc. v.EXELIXIS, INC.

· IPR2025-00210

Azurity Pharmaceuticals failed to convince the PTAB that EXELIXIS's drug formulation patent was unpatentable, resulting in a denial of institution for IPR2025-00210. The Board rejected anticipation arguments based on prior art family relationships and dismissed obviousness claims regarding impurity control.

patent denied · Nov 4, 2024

Helena Laboratories Corporation v.Sebia

· IPR2024-00801

Helena Laboratories Corporation's IPR challenge against Sebia regarding hemoglobin analysis claims was denied by the PTAB. The Board found that the petitioner failed to demonstrate material error in the Examiner's rejection, particularly concerning prior art references like Shihabi and Huang.

patent · Oct 28, 2024

Cipla Limited v.Gilead Sciences, Inc.

· IPR2025-00033

Cipla has filed an IPR petition challenging Gilead’s 2023 ‘802 patent covering a bictegravir/TAF/FTC single‑tablet HIV regimen, asserting obviousness over multiple prior‑art references.

patent denied · Oct 28, 2024

Cipla Limited v.Gilead Sciences, Inc.

· IPR2025-00033

The PTAB denied Cipla Limited's IPR petition against Gilead Sciences regarding patent 11,744,802, citing the advanced stage of parallel district court litigation and lack of compelling merits.

patent · Oct 24, 2024

Dr. Falk Pharma GmbH v.Ellodi Pharmaceuticals LP

· IPR2025-00056

Dr. Falk Pharma has filed an IPR petition seeking cancellation of all 30 claims of Ellodi's 11,260,061 patent covering orally disintegrating corticosteroid tablets. The petition relies on Perrett, Dohil2009, and Venkatesh as prior art to argue obviousness under §103.

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