Industry Sector

Pharmaceuticals — US PTAB Patent Cases

185 decisions indexed

Page 5 of 7 · 185 total

patent · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Merck files a PGR petition challenging Halozyme’s protein‑based contraceptive patent, arguing the claims lack written description and enablement. The reply emphasizes that the specification does not support the broad genus of modified PH20 polypeptides claimed.

patent denied · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

The USPTO Director denied Merck’s request for a review of the PTAB’s institution decisions in four Halozyme patent cases, leaving the institution findings intact.

patent instituted · Dec 11, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00003

Merck Sharp & Dohme LLC successfully challenged Halozyme, Inc.'s patent on modified PH20 polypeptides in a PGR proceeding. The Board found likelihood of prevailing based on arguments regarding the genus's scope and potential lack of enablement/obviousness.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Halozyme seeks Director Review to overturn the PTAB’s institution of a post‑grant review against its hyaluronidase patent, arguing filing‑date errors, improper claim construction, and Fintiv factors favoring denial.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck has filed a petition to invalidate Halozyme’s ’298 patent covering modified PH20 polypeptides, arguing the claims lack written description and enablement. The reply attacks Halozyme’s reliance on functional language and disclaimed dependent claims.

patent instituted · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck challenges Halozyme’s request for Director review after the PTAB instituted a post‑grant review of U.S. Patent 12,018,298 covering modified PH20 polypeptides. Merck argues the eligibility and claim‑construction issues are meritless and that the Fintiv factors favor institution.

patent · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck challenges Halozyme’s broad PH20 hyaluronidase patent, asserting lack of written description, enablement, and obviousness of the claimed protein variants.

patent instituted · Nov 26, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00004

Merck Sharp & Dohme LLC successfully petitioned the PTAB against Halozyme, Inc.'s '298 patent covering modified PH20 polypeptides. The Board granted institution despite challenges based on Written Description and Enablement, allowing the dispute to proceed to trial.

patent denied · Nov 20, 2024

Samsung Bioepis Co., Ltd. v.Regeneron Pharmaceuticals, Inc.

· IPR2025-00176

Samsung Bioepis sought to invalidate numerous claims of Regeneron Pharmaceuticals' ophthalmic formulations using grounds of obviousness (103). The PTAB denied institution based on a holistic Fintiv analysis, citing significant overlap with ongoing district court and MDL proceedings.

patent · Nov 18, 2024

Azurity Pharmaceuticals, Inc. v.EXELIXIS, INC.

· IPR2025-00210

Azurity Pharmaceuticals has filed an IPR petition seeking cancellation of claims 1‑3 of Exelixis’s U.S. Pat. 11,298,349 covering oral cabozantinib (L)-malate formulations. The petition alleges anticipation by the earlier Wilson patent and obviousness over Brown, Kubo and Remington, while arguing that discretionary denial factors do not apply.

patent denied · Nov 18, 2024

Azurity Pharmaceuticals, Inc. v.EXELIXIS, INC.

· IPR2025-00210

Azurity Pharmaceuticals failed to convince the PTAB that EXELIXIS's drug formulation patent was unpatentable, resulting in a denial of institution for IPR2025-00210. The Board rejected anticipation arguments based on prior art family relationships and dismissed obviousness claims regarding impurity control.

patent denied · Nov 4, 2024

Helena Laboratories Corporation v.Sebia

· IPR2024-00801

Helena Laboratories Corporation's IPR challenge against Sebia regarding hemoglobin analysis claims was denied by the PTAB. The Board found that the petitioner failed to demonstrate material error in the Examiner's rejection, particularly concerning prior art references like Shihabi and Huang.

patent · Oct 28, 2024

Cipla Limited v.Gilead Sciences, Inc.

· IPR2025-00033

Cipla has filed an IPR petition challenging Gilead’s 2023 ‘802 patent covering a bictegravir/TAF/FTC single‑tablet HIV regimen, asserting obviousness over multiple prior‑art references.

patent denied · Oct 28, 2024

Cipla Limited v.Gilead Sciences, Inc.

· IPR2025-00033

The PTAB denied Cipla Limited's IPR petition against Gilead Sciences regarding patent 11,744,802, citing the advanced stage of parallel district court litigation and lack of compelling merits.

patent instituted · Oct 24, 2024

Dr. Falk Pharma GmbH v.Ellodi Pharmaceuticals LP

· IPR2025-00056

Dr. Falk Pharma GmbH successfully challenged a pharmaceutical patent (11260061) in an IPR, showing a reasonable likelihood of prevailing on grounds of obviousness (§ 103). The Board's decision hinged on extensive claim construction, particularly defining 'adsorbed onto a pharmaceutically acceptable carrier.'

patent · Oct 12, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00006

Merck’s petition challenges Halozyme’s claims to modified PH20 polypeptides, arguing lack of written description and enablement. The reply reinforces these arguments with case law and scientific exhibits.

patent · Oct 12, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00006

Merck requests Director Review to deny institution of a PTAB post‑grant review of Halozyme’s ‘262 patent covering modified PH20 polypeptides, arguing the Board misapplied eligibility rules and imported a functional limitation into the claim construction.

patent instituted · Oct 12, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00006

Merck defends the institution of a PGR covering modified PH20 enzymes, rejecting Halozyme’s eligibility, claim‑construction, and Fintiv arguments. The response urges the Director to uphold the Board’s earlier institution decision.

patent · Oct 12, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00006

Merck has filed a PGR petition challenging Halozyme’s 13 claims covering PH20 hyaluronidase variants, asserting lack of written description, enablement, and obviousness. The petition seeks to have the claims declared unpatentable.

patent instituted · Oct 12, 2024

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00006

Merck Sharp & Dohme LLC successfully challenged Halozyme, Inc.'s claims regarding modified PH20 polypeptides in a PTAB decision. The Board instituted trial based on enablement and written description grounds, finding that the broad genus of claimed molecules required undue experimentation to identify active variants.

patent · Sep 25, 2024

HIKMA PHARMACEUTICALS USA INC. v.Axsome Malta Ltd. et al.

· IPR2024-01418

Hikma Pharmaceuticals and the patent owners filed a joint motion asking the PTAB to treat their settlement agreement as confidential business information, keeping it separate from the patent file. The request relies on 35 U.S.C. § 317(b) and related regulations.

patent terminated or settled · Sep 25, 2024

HIKMA PHARMACEUTICALS USA INC. v.Axsome Malta Ltd. et al.

· IPR2024-01418

Hikma Pharmaceuticals filed an IPR against Axsome Malta’s 11,560,354 patent. The parties settled the dispute early and jointly moved to terminate the proceeding. The Board granted the motion and ordered the settlement agreement to be kept confidential.

patent terminated or settled · Sep 25, 2024

HIKMA PHARMACEUTICALS USA INC. v.Axsome Malta Ltd. et al.

· IPR2024-01418

Hikma Pharmaceuticals filed a joint motion with Axsome Malta to terminate IPR2024‑01418 after reaching a confidential settlement, resulting in dismissal of the petition before institution.

patent · Sep 25, 2024

HIKMA PHARMACEUTICALS USA INC. v.Axsome Malta Ltd. et al.

· IPR2024-01418

Hikma Pharmaceuticals has filed an IPR petition challenging Axsome’s U.S. Patent 11,560,354 covering solriamfetol compositions. The petition alleges obviousness of claims 1‑8 based on three prior‑art references and argues against discretionary denial of institution.

patent · Aug 21, 2024

Biofrontera Incorporated et al. v.Sun Pharmaceutical Industries, Inc.

· IPR2024-01312

The PTAB has sent a Director Review request to Biofrontera in IPR2024-01312, limiting the petitioner’s response to 15 pages and prohibiting new evidence. The petitioner must respond within five business days.

patent · Aug 2, 2024

Nexus Pharmaceuticals LLC v.Exela Pharma Sciences, LLC

· PGR2024-00016

Nexus Pharmaceuticals has filed a PGR petition challenging all 30 claims of Exela Pharma Sciences' L‑cysteine parenteral nutrition patent, asserting lack of enablement, insufficient written description, and, alternatively, obviousness over the Sandoz label.

patent denied · Aug 2, 2024

Nexus Pharmaceuticals LLC v.Exela Pharma Sciences, LLC

· PGR2024-00016

Nexus Pharmaceuticals' PGR challenge against Exela Pharma Sciences was denied institution because the arguments regarding enablement, written description, and obviousness were largely identical to those previously presented during prosecution. The Board found that the Patent Owner successfully demonstrated how process controls overcome prior rejections, leading to a denial of the petition under § 325(d).

patent instituted · Jul 22, 2024

DR. FALK PHARMA GMBH v.Ellodi Pharmaceuticals LP

· IPR2024-01197

Dr. Falk Pharma GmbH initiated an IPR challenge against Ellodi Pharmaceuticals LP concerning a patent covering oral/topical drug delivery systems. The petition asserts that the challenged claims are obvious under 35 U.S.C. § 103, citing prior art references including Dohil and Grother.

patent final · May 29, 2024

Salvacion USA, Inc. et al. v.Trutek Corp.

· IPR2024-00711

The Petitioner successfully demonstrated that the challenged claims (1-3 and 8) were anticipated by multiple prior art references, including Chen. The Board found that the prior art disclosed all claim elements, leading to a final decision of unpatentability.

patent null · Apr 23, 2024

Encube Ethicals Pvt. Ltd. v.Dermavant Sciences GmbH et al.

· IPR2024-00834

Encube Ethicals Pvt. Ltd. initiated a Petition challenging the validity of Dermavant Sciences GmbH's patent (US 11590088) in the context of psoriasis treatment. The petitioner asserts that the claimed methods are anticipated or obvious based on prior art references like Sonti and Bissonnette.

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