Industry Sector

Pharmaceuticals — US PTAB Patent Cases

247 decisions indexed

Page 1 of 9 · 247 total

patent · Mar 25, 2026

Par Health, Inc. v.InfoRLife, S.A.

· PGR2026-00036

Par Health petitions the PTAB to institute a post‑grant review of U.S. Patent 12,370,153 covering ready‑to‑use ketamine infusion formulations. The petition asserts anticipation by a Biomed data sheet and obviousness over Biomed combined with standard pharmaceutical references and commercial infusion bag literature.

patent · Mar 23, 2026

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· IPR2026-00312

Merck challenges Halozyme’s PH20 enzyme patent, asserting that a 2013 publication anticipates all 18 claims and that the specification lacks written description and enablement. The petition seeks inter partes review under § 102 and § 112(a).

patent · Mar 23, 2026

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· IPR2026-00314

Merck has filed an IPR petition challenging Halozyme’s ’656 patent covering engineered PH20 hyaluronidase proteins. The petition asserts lack of written description and enablement and that US‑275 anticipates all claims.

patent · Mar 20, 2026

Accord BioPharma, Inc. et al. v.Janssen Biotech, Inc. et al.

· IPR2026-00259

Accord BioPharma petitions the PTAB to invalidate claims 1‑7 of Janssen’s anti‑TNF antibody patent, asserting anticipation and obviousness based on Janssen’s own clinical‑trial data and FDA‑approved labeling.

patent · Mar 20, 2026

Accord BioPharma, Inc. et al. v.Janssen Biotech, Inc. et al.

· IPR2026-00256

Accord BioPharma petitions to invalidate claims 1‑10 of US 982, alleging they are anticipated and obvious in view of a Janssen‑sponsored clinical trial and FDA‑approved labeling. The petition seeks institution of an IPR and cancellation of the claims.

patent · Mar 20, 2026

Accord BioPharma, Inc. et al. v.Janssen Biotech, Inc. et al.

· IPR2026-00258

Accord BioPharma has filed an IPR petition seeking to invalidate claims 1‑7 of Janssen’s US 12,122,824 patent covering an IV golimumab regimen for psoriatic arthritis, arguing lack of novelty and obviousness based on a Janssen‑sponsored clinical trial and FDA‑approved labeling.

patent · Mar 20, 2026

Accord BioPharma, Inc. et al. v.Janssen Biotech, Inc. et al.

· IPR2026-00257

Accord BioPharma petitions the PTAB to invalidate Janssen’s golimumab patent (US 11,041,020) on the basis that the claims are anticipated and obvious over the company’s own clinical‑trial protocol and other prior art.

patent · Feb 12, 2026

Merck Sharp & Dohme LLC v.Surrozen Operating, Inc. et al.

· PGR2026-00027

Merck has filed a post‑grant review petition challenging U.S. Patent 12,297,278 covering broad tetravalent Wnt‑surrogate antibodies. The petition asserts lack of written description, enablement, indefiniteness, and anticipation by the Garcia publication.

patent · Feb 10, 2026

Bicara Therapeutics, Inc. v.The John Hopkins University et al.

· PGR2026-00025

Bicara Therapeutics has filed a PTAB Post‑Grant Review petition seeking cancellation of all nine claims of Johns Hopkins' 2025 antibody‑fusion protein patent, alleging lack of written description, lack of enablement, and improper claim dependency.

patent · Feb 4, 2026

Biocon Biologics Limited et al. v.--

· PGR2026-00039

Biocon has filed a PGR petition seeking to invalidate all 38 claims of Regeneron’s ‘036 anti‑VEGF eye‑treatment patent, alleging obviousness over prior art and lack of written description.

patent · Jan 26, 2026

Merck Sharp & Dohme LLC v.Pogona, LLC

· IPR2026-00221

Merck has filed an IPR petition challenging all 19 claims of U.S. Patent 11,058,757, alleging that the pneumococcal vaccine claims are anticipated or obvious in view of Porro, Mekalanos, and Siber. The petition argues examiner error and seeks cancellation of the claims.

patent · Jan 16, 2026

Sun Pharmaceutical Industries, Inc. v.Biofrontera Inc.

· PGR2026-00021

Sun Pharmaceutical has filed a post‑grant review petition seeking cancellation of all 17 claims of Biofrontera’s nanoemulsion patent, alleging anticipation and obviousness over the Uhlmann and Palazzolo prior‑art references.

patent · Dec 23, 2025

Pfizer Inc. v.Pogona, LLC

· IPR2026-00189

Pfizer has filed an IPR petition seeking cancellation of all 19 claims of U.S. Patent 11,058,757 covering pneumococcal conjugate vaccines, arguing that the claims are anticipated or obvious over prior art such as Alexander and Gu, plus extensive epidemiology literature.

patent · Dec 9, 2025

Apotex Inc. v.Ipsen Biopharm Ltd. et al.

· IPR2025-01531

Apotex has filed an IPR petition challenging all 15 claims of Ipsen’s 2017 pancreatic‑cancer treatment patent, arguing the claims are obvious over a body of prior‑art that teaches the same drug regimen.

patent instituted · Dec 9, 2025

Apotex Inc. v.Ipsen Biopharm Ltd. et al.

· IPR2025-01531

The PTAB granted institution for the IPR involving Apotex Inc. and Ipsen Biopharm Ltd., allowing the merits of the challenge to proceed.

patent · Dec 8, 2025

Gilgamesh Pharmaceuticals, Inc. et al. v.Enveric Biosciences Canada, Inc.

· PGR2025-00076

Gilgamesh Pharmaceuticals has petitioned the PTAB to invalidate Enveric Biosciences' 2024 patent covering halogenated psilocybin derivatives, asserting anticipation, obviousness, and lack of enablement for all 26 claims.

patent · Nov 25, 2025

Sarepta Therapeutics, Inc. et al. v.Genzyme Corporation et al.

· IPR2026-00150

Sarepta Therapeutics has filed an IPR petition challenging Genzyme’s ’894 patent covering analytical ultracentrifugation methods for AAV vectors. The petitioner asserts that the claims are obvious in view of long‑standing literature (de la Maza) and the Le Bec patent, combined with Sommer and Cole. The petition seeks institution and cancellation of claims 1‑7 and 10‑30.

patent · Nov 25, 2025

Sarepta Therapeutics, Inc. et al. v.Genzyme Corporation et al.

· IPR2026-00149

Sarepta has petitioned the PTAB to invalidate Genzyme’s ’326 patent on AAV analytical ultracentrifugation, asserting that the claimed methods are obvious in view of earlier publications by Le Bec and de la Maza, supported by Cole and Sommer.

patent · Nov 24, 2025

Ascendis Pharma A/S et al. v.BioMarin Pharmaceutical Inc.

· PGR2026-00013

Ascendis Pharma has filed a PGR petition seeking cancellation of BioMarin’s U.S. Patent 12,331,106 covering CNP‑variant treatments for achondroplasia. The petition alleges obviousness, anticipation, lack of enablement, and an improper dependent claim. The Board must decide whether to institute the review.

patent · Nov 4, 2025

Amneal Pharmaceuticals, Inc. v.Nivagen Pharmaceuticals, Inc.

· IPR2025-00779

Amneal has filed a petition to cancel Nivagen's 11,813,291 patent covering ready‑to‑use potassium phosphate solutions, arguing the claims are obvious over multiple prior‑art references.

patent · Nov 4, 2025

Amneal Pharmaceuticals, Inc. et al. v.Nivagen Pharmaceuticals, Inc.

· IPR2025-00731

Amneal Pharmaceuticals has filed a petition to invalidate all 20 claims of Nivagen’s U.S. Patent 11,925,661 covering ready‑to‑use potassium phosphate solutions, citing multiple prior‑art references and lack of written‑description support.

patent · Nov 2, 2025

Xencor, Inc. v.Merus N.V.

· IPR2025-00605

Xencor has filed an IPR petition challenging all seven claims of Merus’s ’859 bispecific antibody patent, asserting anticipation by Desjarlais and Moore and obviousness over Lazar and Kannan. The petitioner seeks institution and a finding that the claims are unpatentable.

patent instituted · Nov 2, 2025

Xencor, Inc. v.Merus N.V.

· IPR2025-00605

Xencor, Inc. successfully petitioned to institute IPR against Merus N.V.'s patent (11926859) covering heterodimeric antibodies. The Board found reasonable likelihood of unpatentability based on written description and obviousness grounds.

patent instituted · Nov 2, 2025

Xencor, Inc. v.Merus N.V.

· IPR2025-00604

Xencor, Inc. successfully petitioned the PTAB to institute an IPR against Merus N.V.'s patent (9358286) concerning heterodimeric Ig-like molecules. The Board found sufficient evidence of unpatentability under 35 U.S.C. §§ 102 and 103, advancing the dispute into the substantive review phase.

patent terminated or settled · Oct 12, 2025

Atossa Therapeutics, Inc. v.Jina Pharmaceuticals, Inc.

· PGR2026-00015

Atossa Therapeutics and Jina Pharmaceuticals settled their PTAB post‑grant review before trial, leading to a joint motion that terminated the proceeding. The settlement agreement is to remain confidential per the parties' request.

patent · Oct 12, 2025

Atossa Therapeutics, Inc. v.Jina Pharmaceuticals, Inc.

· PGR2026-00015

Atossa Therapeutics and Jina Pharmaceuticals have filed a joint request to keep their settlement agreement confidential and to terminate the pending post‑grant review of U.S. Patent No. 12,245,997. The parties cite statutory confidentiality protections and seek to keep the settlement separate from the PTAB file.

patent · Oct 12, 2025

Atossa Therapeutics, Inc. v.Jina Pharmaceuticals, Inc.

· PGR2026-00015

Atossa Therapeutics and Jina Pharmaceuticals have settled their dispute over U.S. Patent 12,245,997 and filed a joint motion to terminate the post‑grant review. The motion relies on 35 U.S.C. § 327(a) and cites Board precedent for terminating settled proceedings.

patent · Oct 12, 2025

Atossa Therapeutics, Inc. v.Jina Pharmaceuticals, Inc.

· PGR2026-00015

Atossa Therapeutics has filed a Post‑Grant Review petition challenging Jina Pharmaceuticals’ 2025 patent on an endoxifen method for bipolar I disorder. The petition alleges lack of written description, enablement, indefiniteness, and anticipation by prior‑art Ahmad 2016. The case is pending institution.

patent · Oct 11, 2025

Merck Sharp & Dohme LLC v.Halozyme, Inc. et al.

· PGR2025-00087

Merck has filed a post‑grant review petition challenging Halozyme’s U.S. Patent 12,371,685 covering modified PH20 hyaluronidase proteins, asserting lack of written description and enablement.

patent · Oct 6, 2025

United Therapeutics Corporation v.Actelion Pharmaceuticals Ltd. et al.

· IPR2025-01139

United Therapeutics has filed an IPR petition seeking cancellation of all 57 claims of Actelion’s ’847 patent covering macitentan‑PDE5 inhibitor combinations for pulmonary hypertension. The petition alleges anticipation by Bolli and obviousness over Bolli‑Keyser and Hoeper‑Morice references, arguing that secondary considerations are irrelevant.

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