Industry Sector

Pharmaceuticals — US PTAB Patent Cases

247 decisions indexed

Page 8 of 9 · 247 total

patent instituted · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00623

Merck Sharp & Dohme LLC successfully secured institution for its IPR challenge against The Johns Hopkins University regarding oncology/immunotherapy claims. The Board found sufficient evidence to proceed under 35 U.S.C. § 102 and § 103, despite procedural challenges from the Patent Owner.

patent instituted · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00622

Merck Sharp & Dohme LLC successfully convinced the PTAB to institute IPR proceedings against The Johns Hopkins University regarding anti-cancer therapies using PD-1 blockade. The Board found sufficient evidence that prior art, including the MSI-H Study Record, renders several claims unpatentable.

patent Final Written Decision · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00625

The PTAB issued a Final Written Decision finding that claims 1-8 of the patent were unpatentable. The Petitioner successfully demonstrated that the MSI-H Study Record (MSR) anticipates and renders obvious most challenged claims under both § 102 and § 103. The Board ruled that the Patent Owner's objective evidence of non-obviousness was insufficient to overcome these findings.

patent Final Written Decision · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00623

The PTAB issued a Final Written Decision finding that all seven claims of the patent were unpatentable. The petitioner successfully demonstrated anticipation (102) and obviousness (103) based on the MSI-H Study Record, which was deemed prior art despite arguments regarding experimental use exceptions.

patent Final Written Decision · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00624

The PTAB issued a Final Written Decision finding multiple claims of the '975 patent unpatentable. The petitioner successfully demonstrated that the claimed methods and drug characteristics were anticipated (102) or rendered obvious (103) by prior art, primarily the MSI-H Study Record (MSR).

patent final · Apr 3, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00622

The PTAB found all 28 challenged claims unpatentable in this IPR proceeding concerning oncology/immunotherapy. The Petitioner successfully demonstrated that the MSI-H Study Record inherently anticipated or rendered obvious the claimed methods under both § 102 and § 103.

patent · Mar 26, 2024

Ovid Therapeutics Inc. v.Marinus Pharmaceuticals, Inc.

· IPR2024-00726

Marinus Pharmaceuticals seeks to invalidate Ovid Therapeutics’ 2022 ganaxolone patent covering methods for treating status epilepticus, arguing anticipation, obviousness, and lack of enablement based on prior publications and press releases.

patent null · Mar 26, 2024

Ovid Therapeutics Inc. v.Marinus Pharmaceuticals, Inc.

· IPR2024-00726

Ovid Therapeutics challenges Marinus Pharmaceuticals' patent on ganaxolone, arguing that all claims are obvious over various combinations of clinical trial data and earlier patents. The petitioner asserts that prior art provides sufficient motivation for treating status epilepticus (SE) with the claimed dosing regimen.

patent denied · Mar 26, 2024

Ovid Therapeutics Inc. v.Marinus Pharmaceuticals, Inc.

· IPR2024-00726

Ovid Therapeutics Inc.'s IPR challenge against Marinus Pharmaceuticals, Inc. was denied by the PTAB on grounds of obviousness (103). The Board found that Petitioner failed to demonstrate a reasonable likelihood of prevailing in its challenges regarding plasma concentration limitations and priority.

patent null · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00650

Merck Sharp & Dohme LLC petitioned to invalidate U.S. Patent No. 11,634,491 on grounds of anticipation and obviousness in the field of Oncology/Immunotherapy. The petitioner argues that key claims are anticipated by the MSI-H Study Record (EX1005) under 35 U.S.C. § 102. Furthermore, the remaining claims are deemed obvious when combining the MSI-H Study Record with various prior art references like Brown, Duval, Benson, and Koh under 35 U.S.C. § 103.

patent null · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00649

Merck Sharp & Dohme LLC challenges U.S. Patent No. 11,629,187 in an IPR proceeding before the PTAB. The petitioner argues that all claims are unpatentable under both anticipation (35 U.S.C. § 102) and obviousness (35 U.S.C. § 103).

patent null · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00648

Merck Sharp & Dohme LLC challenged U.S. Patent No. 11,643,462 in the PTAB, arguing that all claims are anticipated under 35 U.S.C. § 102 and rendered obvious under 35 U.S.C. § 103. The petitioner asserts that the MSI-H Study Record discloses the claimed method of treating MSI-H cancer with pembrolizumab, leading to a request for institution based on compelling evidence.

patent null · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00647

Merck Sharp & Dohme LLC challenges The Johns Hopkins University's patent (11,649,287) in an IPR proceeding based on anticipation and obviousness. Petitioner asserts that the MSI-H Study Record discloses all claimed methods, rendering the claims unpatentable under 35 U.S.C. § 102 and § 103. The petitioner argues for discretionary denial of institution is inappropriate given the prior art's relevance to the patent's scope.

patent instituted · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00650

Merck Sharp & Dohme LLC successfully challenged The Johns Hopkins University's patent (11634491) in a PTAB Institution Decision. The Board found reasonable likelihood of success for multiple claims under both anticipation (§ 102) and obviousness (§ 103).

patent instituted · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00649

Merck Sharp & Dohme LLC successfully challenged The Johns Hopkins University's patent claims regarding MSI-H cancer treatment, leading the PTAB to institute proceedings. The petitioner argued that the claimed methods were anticipated by or obvious over existing prior art, including the MSI-H Study Record and various medical literature.

patent instituted · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00648

Merck Sharp & Dohme LLC successfully petitioned to institute IPR proceedings against The Johns Hopkins University regarding a patent on immunotherapy methods. The Board found reasonable likelihood of unpatentability under both 102 and 103, primarily based on the MSI-H Study Record.

patent instituted · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00647

Merck Sharp & Dohme LLC successfully petitioned to institute IPR against The Johns Hopkins University regarding claims related to anti-PD-1 antibody treatment for MSI colorectal cancer. The Board found a reasonable likelihood of success under both 102 and 103 grounds across all 36 claims at issue.

patent Final Written Decision · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00650

The PTAB issued a Final Written Decision finding all 38 claims of the '491 patent unpatentable. The Board construed "in response to" as requiring a causal link between MSI-H/dMMR determination and treatment, which led to a finding that the MSR anticipated and rendered obvious the challenged claims.

patent final · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00649

The PTAB found that the patent claims were unpatentable under both anticipation (35 U.S.C. § 102) and obviousness (35 U.S.C. § 103). The Board concluded that the MSI-H Study Record anticipates the claimed invention by teaching all elements, leading to a final decision against the patent owner.

patent final · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00648

The PTAB found all 30 challenged claims unpatentable by anticipation (102) and obviousness (103). The Petitioner successfully argued that the MSI-H Study Record anticipates the claimed methods for treating non-colorectal MSI-H cancers.

patent final · Mar 13, 2024

Merck Sharp & Dohme LLC et al. v.The Johns Hopkins University

· IPR2024-00647

The PTAB found all 36 challenged claims unpatentable by both anticipation (35 U.S.C. § 102) and obviousness (35 U.S.C. § 103). The Board concluded that the MSI-H Study Record inherently anticipates the claimed methods, including those requiring pre-treatment testing for microsatellite instability high or DNA mismatch repair deficient status. This decision significantly weakens the patent's validity in the context of oncology and immunotherapy.

patent · Feb 21, 2024

Dr. Reddy's Laboratories S.A. et al. v.Eye Therapies, LLC et al.

· IPR2024-00563

Dr. Reddy’s Laboratories and Eye Therapies jointly request that their settlement agreement be kept confidential and separate from the IPR patent file.

patent terminated or settled · Feb 21, 2024

Dr. Reddy's Laboratories S.A. et al. v.Eye Therapies, LLC et al.

· IPR2024-00563

Dr. Reddy’s Laboratories and Eye Therapies have settled their dispute over U.S. Patent 11,596,600 and jointly moved to terminate the inter partes review.

patent terminated or settled · Feb 21, 2024

Dr. Reddy's Laboratories S.A. et al. v.Eye Therapies, LLC et al.

· IPR2024-00563

Dr. Reddy’s and Eye Therapies settled their IPR dispute, resulting in a joint motion that terminated the proceedings. The Board granted the termination and kept the settlement confidential.

patent instituted · Feb 21, 2024

Sarepta Therapeutics, Inc et al. v.The Trustees of the University of Pennsylvania et al.

· IPR2024-00580

Sarepta Therapeutics challenged patent 11680274, owned by The Trustees of the University of Pennsylvania and Regenxbio Inc., on grounds of obviousness (103). The PTAB ruled in favor of institution, finding that the challenger's arguments were strong enough to warrant further review.

patent null · Feb 21, 2024

Dr. Reddy's Laboratories S.A. et al. v.Eye Therapies, LLC et al.

· IPR2024-00563

Dr. Reddy's Laboratories challenges the patentability of U.S. Patent No. 11,596,600 regarding brimonidine eye drops using obviousness over prior art. The Petition argues that a Person of Ordinary Skill in the Art (POSA) would have been motivated to use low concentrations for treating ocular redness. The Board is urged to deny institution based on Hatch-Waxman goals and alleged Examiner error.

patent instituted · Feb 21, 2024

Sarepta Therapeutics, Inc et al. v.The Trustees of the University of Pennsylvania et al.

· IPR2024-00580

Sarepta Therapeutics, Inc. successfully challenged several claims of The Trustees of the University of Pennsylvania in an IPR proceeding regarding gene therapy/AAV technology. The Board found a reasonable likelihood of prevailing on multiple grounds of obviousness (35 U.S.C. § 103) using combinations of prior art references.

patent instituted · Feb 21, 2024

Dr. Reddy's Laboratories S.A. et al. v.Eye Therapies, LLC et al.

· IPR2024-00563

The PTAB instituted the IPR petition challenging key claims of a patent related to vasoconstriction agents for eye redness. The Board found that Petitioner demonstrated a reasonable likelihood of prevailing, despite arguments from the Patent Owner regarding prior art limitations and adverse events.

patent Final Written Decision · Feb 21, 2024

Sarepta Therapeutics, Inc et al. v.The Trustees of the University of Pennsylvania et al.

· IPR2024-00580

The Board issued a Final Written Decision upholding the validity of claim 8 in this gene therapy IPR. The decision found that Petitioner failed to demonstrate sufficient motivation or reasonable expectation of success to combine prior art references under 35 U.S.C. § 103(a).

patent instituted · Feb 12, 2024

Formycon AG v.Regeneron Pharmaceuticals, Inc.

· IPR2025-00233

Formycon secured an institution of IPR against Regeneron's VEGF‑antagonist formulation patent (10,464,992), covering claims 1‑18, after the Board found a reasonable likelihood of success.

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