Industry Sector

Biotechnology — US PTAB Patent Cases

40 decisions indexed

Page 1 of 2 · 40 total

patent instituted

Alamar Biosciences, Inc. v.Olink Proteomics AB et al.

· IPR2024-01353

Alamar Biosciences challenged Olink Proteomics' patent on grounds of obviousness (103), leading the PTAB to institute proceedings for claims 1-20. The Board found sufficient evidence that at least some claimed inventions are unpatentable, initiating a trial phase.

patent denied

Guardant Health, Inc. v.Cold Spring Harbor Laboratory

· IPR2025-01355

The PTAB denied Guardant Health's IPR challenge against Cold Spring Harbor Laboratory's patent, finding the petitioner failed to show a reasonable likelihood of prevailing on any challenged claims.

patent final

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-00965

The PTAB found all six challenged claims unpatentable due to anticipation and obviousness. The Board determined that the prior art reference Gloor anticipates every claim (1-6). Furthermore, combinations of Parameswaran with other references rendered the remaining claims obvious.

patent final

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-00964

The PTAB issued a Final Written Decision rejecting the Petitioner's challenge to claims 1-8 of U.S. Patent No. 11041852. The Board adopted the Patent Owner’s narrow construction of 'cross-over error,' limiting it specifically to errors during cluster amplification, and found no anticipation or obviousness over cited prior art.

patent instituted

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-00965

Illumina successfully secured the institution of Inter Partes Review against Molecular Loop Biosciences' patent, challenging claims 1-6 based on anticipation by Gloor and obviousness over multiple prior art references.

patent instituted

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-00964

Illumina successfully petitioned the PTAB to institute an IPR against Molecular Loop Biosciences regarding next-generation sequencing technology. The Board found a reasonable likelihood of obviousness over Parameswaran and Gloor, allowing the case to proceed to trial.

patent final

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-01419

The PTAB upheld the patentability of claims 1-9 for Molecular Loop Biosciences against Illumina. The Board rejected all grounds of anticipation and obviousness over prior art like Chee, finding that the required 'collapsing step' necessitates combining both target sequence and differentiator tag information.

patent instituted

Bruker Spatial Biology, Inc. v.10x Genomics, Inc. et al.

· IPR2024-00526

Bruker Spatial Biology successfully petitioned the PTAB to institute an IPR against 10x Genomics, Inc., challenging numerous claims of patent 11542554. The Board found a reasonable likelihood that the challenged claims are unpatentable based on grounds of obviousness (35 U.S.C. § 103).

patent final

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2025-00016

The PTAB issued a final written decision rejecting all grounds of unpatentability asserted by the Petitioner regarding NGS target enrichment claims. The Board adopted the Patent Owner's narrow definition of 'enrichment,' finding that the prior art failed to teach the claimed proportional increase in target fragments.

patent final

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2025-00015

The PTAB upheld the patent against IPR challenges related to NGS target enrichment. The Board clarified that 'enrichment' requires an increased proportion of the sequence relative to others, not just a raw increase in fragment count. Petitioner failed to meet its burden of proof on unpatentability.

patent final

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2024-01504

The PTAB found multiple claims unpatentable under both § 102 (anticipation) and § 103 (obviousness). The decision centered on the combination of prior art references—specifically Iafrate, Kivioja, and Bielas—in the context of Next Generation Sequencing (NGS) technologies. Claim construction was finalized, defining key terms like 'identifier site' and 'indexing site'.

patent final

PreOmics GmbH et al. v.The Brigham and Women’s Hospital, Inc.

· IPR2024-01473

The Board found that six claims (1, 4, 6, 17, 22, and 25) of the patent were unpatentable based on anticipation by prior art Cai. The decision hinged on a broad interpretation of key terms like 'biological sample' and 'subset of particles,' which favored the Petitioner's arguments regarding the scope of the claims.

patent final

Bio-Rad Laboratories, Inc. v.California Institute of Technology et al.

· IPR2024-01451

The PTAB issued a Final Written Decision rejecting all claims (1-19) of the '921 patent. The Board rejected arguments based on obviousness and novelty, particularly concerning multi-occupancy droplet detection in multiplexed biochemical assays.

patent final

Alamar Biosciences, Inc. v.Olink Proteomics AB et al.

· IPR2024-01353

The petitioner failed to prove the obviousness of claims 1-20 of U.S. Patent No. 7883848 in a Final Written Decision. The Board adopted a specific claim construction for 'selecting all cis-reactive cells exhibiting the detectable trace,' defining it as selecting associations of at least two interactor moieties joined by an associated oligonucleotide that exhibit the detectable trace.

patent denied

Bio-Rad Laboratories, Inc. v.California Institute of Technology et al.

· IPR2024-01177

Bio-Rad Laboratories, Inc. failed to institute an IPR against California Institute of Technology et al.'s patent covering multiplexed analyte detection. The Board found that the Petitioner did not provide sufficient support for key disclosures in the asserted prior art (Saxonov) during the initial petition phase.

patent denied

Bio-Rad Laboratories, Inc. v.California Institute of Technology et al.

· IPR2024-01178

Bio-Rad Laboratories, Inc.'s IPR challenge against California Institute of Technology et al. was denied by the PTAB. The Board found that the Petitioner failed to demonstrate sufficient support for key prior art disclosures in Saxonov from the provisional application, leading to a failure to establish unpatentability under 35 U.S.C. 103(a).

patent denied

Bio-Rad Laboratories, Inc. v.California Institute of Technology et al.

· IPR2024-01178

The PTAB denied Bio-Rad Laboratories' request for rehearing regarding the denial of institution in IPR2024-01178, upholding its finding that the petitioner failed to meet the burden of proving unpatentability.

patent

Ecto World, LLC d/b/a Demand Vape et al. v.RAI Strategic Holdings, Inc. et al.

· IPR2024-01280

The Director granted review in an IPR case (IPR2024-01280), vacating the denial of institution. The proceeding is remanded for parties to clarify arguments regarding discretionary denial under 35 U.S.C. § 325(d) and parallel ITC litigation.

patent denied

Curio Bioscience et al. v.Prognosys Biosciences Inc. et al.

· IPR2024-01289

The PTAB denied the IPR petition brought by Curio Bioscience against Prognosys and 10X Genomics, finding that the challenged claims were not obvious over Cantor or anticipated by Frisen. The Board upheld the Patent Owner's position regarding spatial analysis in tissue samples.

patent instituted

Illumina, Inc. v.Molecular Loop Biosciences, Inc.

· IPR2024-01419

Illumina successfully petitioned the PTAB to institute trial against Molecular Loop Biosciences' patent claims related to genomic sequencing and analysis. The Board found a reasonable likelihood of prevailing on at least claim 1, allowing the IPR to proceed despite extensive prior art challenges under Sections 102 and 103.

patent instituted

Bio-Rad Laboratories, Inc. v.California Institute of Technology et al.

· IPR2024-01451

Bio-Rad Laboratories successfully secured the institution of its IPR against California Institute of Technology's patent, challenging claims based on anticipation and obviousness. The Board found that Bio-Rad demonstrated a reasonable likelihood of prevailing regarding Claim 1 over Larson.

patent instituted

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2024-01502

Integrated DNA Technologies challenged Tecan Genomics's NGS patent (9546399) on grounds of anticipation and obviousness over prior art references Iafrate and Kivioja. The PTAB instituted the IPR, finding a reasonable likelihood that at least one claim is unpatentable under 35 U.S.C. § 103 over Iafrate and Kivioja.

patent instituted

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2024-01504

The PTAB instituted the IPR, finding a reasonable likelihood of unpatentability based on obviousness over Iafrate and Kivioja for key NGS claims. The Board also provided definitive claim constructions for 'indexing site' and 'identifier site.'

patent instituted

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2024-01506

The PTAB granted institution for an IPR challenging claims 1-16 of a nucleic acid analysis patent, finding reasonable likelihood of success. The Board rejected the Patent Owner's motion to deny based on prior art similarity, allowing the technical merits of anticipation and obviousness over Kivioja and Bielas to proceed to trial.

patent instituted

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2025-00015

Integrated DNA Technologies successfully petitioned IPR against Tecan Genomics' NGS patent (US 10036012), showing a reasonable likelihood that prior art (Meyer) anticipates claims. The Board granted institution, setting the stage for a full trial on all 22 challenged claims.

patent instituted

Integrated DNA Technologies, Inc. et al. v.Tecan Group AG

· IPR2025-00016

Integrated DNA Technologies successfully challenged the '108 patent's claims in a PTAB institution decision, finding reasonable likelihood of prevailing on anticipation for Claim 1. The Board affirmed that prior art disclosure was sufficient to support the enrichment limitation using Meyer et al.

patent instituted

QIAGEN Sciences, LLC v.Tecan Group AG

· IPR2025-00026

QIAGEN Sciences successfully convinced the PTAB to institute trial proceedings against Tecan Genomics, Inc. regarding a high-throughput sequencing patent (11098357). The Board found reasonable likelihood that claims 1 through 10 are unpatentable under both anticipation (§ 102) and obviousness (§ 103).

patent instituted

QIAGEN Sciences, LLC v.Tecan Group AG

· IPR2025-00027

QIAGEN Sciences successfully petitioned to institute IPR proceedings against Tecan Genomics for patent number 11725241. The Board found sufficient evidence of unpatentability across multiple claims based on grounds of anticipation (35 U.S.C. § 102) and obviousness (35 U.S.C. § 103).

patent instituted

QIAGEN Sciences, LLC v.Tecan Group AG

· IPR2025-00028

QIAGEN Sciences successfully petitioned the PTAB against Tecan Genomics regarding claims related to Next-Generation Sequencing (NGS). The Board instituted review, finding a reasonable likelihood of prevailing on obviousness grounds.

patent instituted

QIAGEN Sciences, LLC v.Tecan Group AG

· IPR2025-00029

QIAGEN Sciences successfully petitioned to institute IPR proceedings against Tecan Genomics, challenging claims of U.S. Patent No. 10876108 based on obviousness (35 U.S.C. § 103). The Board found that the Examiner erred in relying solely on secondary considerations, adopting the Petitioner's view that combining Shapero and Delseny renders multiple claims obvious.

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